SAR125844
SAR125844 is a potent and selective small molecule inhibitor of the MET receptor tyrosine kinase, exhibiting an IC50 of 4.2 nM. It is utilized in preclinical research to investigate MET-driven oncogenesis and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1116743-46-4
Product Name Alternative
Inhibit, Inhibitor, MET RTK, HGFR, Apoptosis, c-Met, cMet/HGFR, cMet, c-Met/HGFR, SAR125844, SAR-125844, SAR125884, SAR-125884, SAR 125844, SAR 125884
Field of Research
Cell Biology, Signal Transduction
Purity
98.39% (May vary between batches)
Solubility
DMSO:45 mg/mL (81.72 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (3.63 mM)
Smiles
Fc1ccc (cc1) -c1ccc2nnc (Sc3ccc4nc (NC (=O) NCCN5CCOCC5) sc4c3) n2n1
Molecular Formula
C25H23FN8O2S2
Molecular Weight
550.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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