Imidazole ketone erastin
Imidazole ketone erastin (IKE) is a small molecule ferroptosis inducer that inhibits the system Xc- transporter, leading to cystine deprivation, glutathione depletion, and lethal lipid peroxidation. It is widely used in vitro and in vivo to investigate ferroptosis mechanisms and evaluate antitumor strategies in cancer research.
Product Specifications
CAS Number
1801530-11-9
Product Name Alternative
Ferroptosis, IKE, Imidazole ketone erastin
Field of Research
Cell Biology
Purity
98.48% (May vary between batches)
Solubility
DMSO:100 mg/mL (152.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.11 mM)
Smiles
CC (C) Oc1ccc (cc1-n1c (CN2CCN (CC2) C (=O) COc2ccc (Cl) cc2) nc2ccccc2c1=O) C (=O) Cn1ccnc1
Molecular Formula
C35H35ClN6O5
Molecular Weight
655.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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