GSK1904529A
GSK1904529A is a potent dual inhibitor of IGF-1R and IR with IC50 values of 27 nM and 25 nM, respectively. This small molecule is a valuable research tool for studying insulin/IGF-1 signaling pathways in cancer and metabolic disease research, with demonstrated utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1089283-49-7
Product Name Alternative
B-Raf (V600E), Apoptosis, anti-tumor, inhibit, Inhibitor, GSK4529, GSK-4529, GSK1904529A, GSK-1904529A, GSK 4529, IGF-1R, IGF1R, insulin, Insulin Receptor, Syk, VEGFR2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.20% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.7 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:16.11 mg/mL (18.91 mM)
Smiles
CCc1cc (Nc2nccc (n2) -c2c (nc3ccccn23) -c2ccc (OC) c (c2) C (=O) Nc2c (F) cccc2F) c (OC) cc1N1CCC (CC1) N1CCN (CC1) S (C) (=O) =O
Molecular Formula
C44H47F2N9O5S
Molecular Weight
851.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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