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GSK1904529A

GSK1904529A is a potent dual inhibitor of IGF-1R and IR with IC50 values of 27 nM and 25 nM, respectively. This small molecule is a valuable research tool for studying insulin/IGF-1 signaling pathways in cancer and metabolic disease research, with demonstrated utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1089283-49-7

Product Name Alternative

B-Raf (V600E), Apoptosis, anti-tumor, inhibit, Inhibitor, GSK4529, GSK-4529, GSK1904529A, GSK-1904529A, GSK 4529, IGF-1R, IGF1R, insulin, Insulin Receptor, Syk, VEGFR2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

98.20% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.7 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:16.11 mg/mL (18.91 mM)

Smiles

CCc1cc (Nc2nccc (n2) -c2c (nc3ccccn23) -c2ccc (OC) c (c2) C (=O) Nc2c (F) cccc2F) c (OC) cc1N1CCC (CC1) N1CCN (CC1) S (C) (=O) =O

Molecular Formula

C44H47F2N9O5S

Molecular Weight

851.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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