KN1022
KN1022 is a potent small molecule inhibitor that selectively targets the platelet-derived growth factor (PDGF) receptor, blocking its phosphorylation with an IC50 of 0.26 μM. It is a valuable research tool for studying PDGF signaling pathways in cellular models and has been utilized in investigations related to fibrosis and proliferative diseases.
Product Specifications
CAS Number
205255-11-4
Product Name Alternative
PDGFR, KN1022, KN-1022, KN 1022
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.68% (May vary between batches)
Solubility
DMSO:11 mg/mL (25.09 mM)
Smiles
O (C) C1=CC=2C (=NC=NC2C=C1OC) N3CCN (C (NC4=CC=C (N (=O) =O) C=C4) =O) CC3
Molecular Formula
C21H22N6O5
Molecular Weight
438.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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