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KN1022

KN1022 is a potent small molecule inhibitor that selectively targets the platelet-derived growth factor (PDGF) receptor, blocking its phosphorylation with an IC50 of 0.26 μM. It is a valuable research tool for studying PDGF signaling pathways in cellular models and has been utilized in investigations related to fibrosis and proliferative diseases.

Product Specifications

CAS Number

205255-11-4

Product Name Alternative

PDGFR, KN1022, KN-1022, KN 1022

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.68% (May vary between batches)

Solubility

DMSO:11 mg/mL (25.09 mM)

Smiles

O (C) C1=CC=2C (=NC=NC2C=C1OC) N3CCN (C (NC4=CC=C (N (=O) =O) C=C4) =O) CC3

Molecular Formula

C21H22N6O5

Molecular Weight

438.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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