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USP5-IN-1

USP5-IN-1 (compound 64) is a selective small molecule inhibitor targeting the ZnF-UBD domain of deubiquitinase USP5 with a KD of 2.8 μM. It blocks USP5's catalytic activity against di-ubiquitin substrates and serves as a valuable chemical probe for in vitro studies investigating ubiquitin signaling and cancer-related pathways.

Product Specifications

Product Name Alternative

USP5, USP5IN1, USP5-IN-1

Field of Research

Cell Biology, Molecular Biology, Protein Biochemistry

Purity

99.53% (May vary between batches)

Solubility

DMSO:48.33 mg/mL (110.37 mM)

Smiles

O=C (O) CNC (=O) C1=CC=C (S (=O) (=O) N2CCC (C3=CC=C (Cl) C=C3) CC2) C=N1

Molecular Formula

C19H20ClN3O5S

Molecular Weight

437.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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