USP8-IN-1
USP8-IN-1 is a small molecule inhibitor of the deubiquitinase USP8, exhibiting an IC50 of 1.9 μM. It demonstrates anti-proliferative activity in cellular assays, such as in H1975 lung cancer cells with a GI50 of 82.04 μM. This compound is a useful research tool for studying USP8's role in oncology and EGFR signaling pathways.
Product Specifications
CAS Number
2477650-96-5
Product Name Alternative
USP8, USP8-IN-1, USP8inhibitor
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.01% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (290.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.32 mM)
Smiles
COc1ccc (N2CCN (CC2) C (=S) Nc2ccc (cc2) [N+] ([O-]) =O) c (N) c1
Molecular Formula
C18H21N5O3S
Molecular Weight
387.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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