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MSC-4106

MSC-4106 is a potent, orally bioavailable small molecule inhibitor of the YAP/TAZ-TEAD interaction. It functions by blocking the auto-palmitoylation of TEAD1 and TEAD3 transcription factors, and it has shown significant anti-tumor efficacy in the NCI-H226 mesothelioma xenograft model, supporting its use in cancer research.

Product Specifications

CAS Number

2738542-58-8

Product Name Alternative

YAP–TEAD, MSC 4106, MSC4106, MSC-4106

Field of Research

Stem Cell & Developmental Biology

Purity

99.89% (May vary between batches)

Solubility

DMSO:225 mg/mL (626.22 mM)

Smiles

Cn1cc2c3cc (ccc3n (-c3ccc (cc3) C (F) (F) F) c2n1) C (O) =O

Molecular Formula

C18H12F3N3O2

Molecular Weight

359.3

Storage Conditions

-20°C

Notes

For research use only.

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