MSC-4106
MSC-4106 is a potent, orally bioavailable small molecule inhibitor of the YAP/TAZ-TEAD interaction. It functions by blocking the auto-palmitoylation of TEAD1 and TEAD3 transcription factors, and it has shown significant anti-tumor efficacy in the NCI-H226 mesothelioma xenograft model, supporting its use in cancer research.
Product Specifications
CAS Number
2738542-58-8
Product Name Alternative
YAP–TEAD, MSC 4106, MSC4106, MSC-4106
Field of Research
Stem Cell & Developmental Biology
Purity
99.89% (May vary between batches)
Solubility
DMSO:225 mg/mL (626.22 mM)
Smiles
Cn1cc2c3cc (ccc3n (-c3ccc (cc3) C (F) (F) F) c2n1) C (O) =O
Molecular Formula
C18H12F3N3O2
Molecular Weight
359.3
Storage Conditions
-20°C
Notes
For research use only.
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