Zosuquidar
Zosuquidar is a potent P-glycoprotein inhibitor that suppresses tumor growth. It also promotes the autophagic degradation of PD-L1, reducing its expression. This small molecule is utilized in oncology research, particularly in studies of multidrug resistance and acute myeloid leukemia, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
167354-41-8
Product Name Alternative
RS33295-198, RS 33295-198, Zosuquidar, LY335979, LY-335979
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.44% (May vary between batches)
Solubility
DMSO:80 mg/mL (151.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.48 mM)
Smiles
FC1 (F) [C@]2 ([C@@]1 (C=3C ([C@@H] (C=4C2=CC=CC4) N5CCN (C[C@H] (COC=6C7=C (C=CC6) N=CC=C7) O) CC5) =CC=CC3) [H]) [H]
Molecular Formula
C32H31F2N3O2
Molecular Weight
527.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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