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CB-5339

P97-IN-1 is a highly potent small molecule inhibitor of the p97 ATPase, demonstrating inhibitory activity with an IC50 below 30 nM. This compound is a valuable research tool for investigating p97 function in protein homeostasis, with applications in both cellular and biochemical studies relevant to cancer and neurodegenerative disease research.

Product Specifications

CAS Number

1863952-15-1

Product Name Alternative

P97, CB5339, CB-5339, CB 5339, 1HIndole4carboxamide,2methyl1[5,6,7,8tetrahydro4[ (phenylmethyl) amino]pyrido[2,3d]pyrimidin2yl]

Field of Research

Protein Biochemistry

Purity

97.66% (May vary between batches)

Solubility

DMSO:50 mg/mL (121.22 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.06 mM)

Smiles

CC=1N (C=2C (=C (C (N) =O) C=CC2) C1) C3=NC (NCC4=CC=CC=C4) =C5C (N3) =NCCC5

Molecular Formula

C24H24N6O

Molecular Weight

412.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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