CB-5339
P97-IN-1 is a highly potent small molecule inhibitor of the p97 ATPase, demonstrating inhibitory activity with an IC50 below 30 nM. This compound is a valuable research tool for investigating p97 function in protein homeostasis, with applications in both cellular and biochemical studies relevant to cancer and neurodegenerative disease research.
Product Specifications
CAS Number
1863952-15-1
Product Name Alternative
P97, CB5339, CB-5339, CB 5339, 1HIndole4carboxamide,2methyl1[5,6,7,8tetrahydro4[ (phenylmethyl) amino]pyrido[2,3d]pyrimidin2yl]
Field of Research
Protein Biochemistry
Purity
97.66% (May vary between batches)
Solubility
DMSO:50 mg/mL (121.22 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.06 mM)
Smiles
CC=1N (C=2C (=C (C (N) =O) C=CC2) C1) C3=NC (NCC4=CC=CC=C4) =C5C (N3) =NCCC5
Molecular Formula
C24H24N6O
Molecular Weight
412.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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