TAS1553
TAS1553 is a potent, orally bioavailable small molecule PPI inhibitor (IC50 = 39.6 nM) that disrupts DNA replication by depleting dATP, leading to apoptosis. It is a valuable research tool for investigating cancer therapeutics in both cellular and in vivo models.
Product Specifications
CAS Number
2166023-31-8
Product Name Alternative
TAS 1553, TAS1553, TAS-1553, protein–protein interaction (PPI)
Field of Research
Cell Biology
Purity
97.03% (May vary between batches)
Solubility
DMSO:90 mg/mL (186.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.83 mM)
Smiles
C[C@@H] ([C@H] (NS (=O) (=O) c1ccc (Cl) cc1C (N) =O) c1n[nH]c (=O) o1) c1c (F) ccc (C) c1C
Molecular Formula
C20H20ClFN4O5S
Molecular Weight
482.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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