YAP/TAZ inhibitor-2
YAP/TAZ inhibitor-2 is a potent, orally bioavailable small molecule that disrupts the TEAD-YAP/TAZ interaction with an EC50 of 3 nM. It demonstrates robust anti-proliferative effects in cellular assays and has shown promising antitumor activity in vivo, making it a valuable chemical probe for Hippo pathway and cancer research.
Product Specifications
CAS Number
2762617-31-0
Product Name Alternative
YAP/TAZ inhibitor-2, YAP/TAZinhibitor2 , YAP–TEAD
Field of Research
Cancer Biology; Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.65% (May vary between batches)
Solubility
DMSO:90 mg/mL (230.57 mM)
Smiles
FC (=C) C (=O) N1CC (C1) n1nc (-c2ccc (cc2) C (F) (F) F) c2cccnc12
Molecular Formula
C19H14F4N4O
Molecular Weight
390.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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