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YAP/TAZ inhibitor-2

YAP/TAZ inhibitor-2 is a potent, orally bioavailable small molecule that disrupts the TEAD-YAP/TAZ interaction with an EC50 of 3 nM. It demonstrates robust anti-proliferative effects in cellular assays and has shown promising antitumor activity in vivo, making it a valuable chemical probe for Hippo pathway and cancer research.

Product Specifications

CAS Number

2762617-31-0

Product Name Alternative

YAP/TAZ inhibitor-2, YAP/TAZinhibitor2 , YAP–TEAD

Field of Research

Cancer Biology; Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.65% (May vary between batches)

Solubility

DMSO:90 mg/mL (230.57 mM)

Smiles

FC (=C) C (=O) N1CC (C1) n1nc (-c2ccc (cc2) C (F) (F) F) c2cccnc12

Molecular Formula

C19H14F4N4O

Molecular Weight

390.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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