DYRK1-IN-1
DYRK1-IN-1 is a potent, selective, and ligand-efficient inhibitor of DYRK1A (IC50 = 220 nM) . It demonstrates favorable cell permeability and CNS penetrance without P-gp efflux, making it a valuable chemical probe for studying DYRK1A's role in neurobiology and related diseases in both cellular and in vivo models.
Product Specifications
CAS Number
2814486-79-6
Field of Research
Cell Biology, Signal Transduction
Smiles
N (C) (C) C=1N=C (C2=C3N (N=C2) N=CC=C3) C=CN1
Molecular Formula
C12H12N6
Molecular Weight
240.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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