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CCR4 antagonist 3-1

CCR4 antagonist 3-1 is a small molecule inhibitor of the CCR4 chemokine receptor, demonstrating activity in vitro by blocking TARC and MDC ligand binding (IC50 = 1.7 μM) and inhibiting TARC-mediated cell migration (IC50 = 6.4 μM) . This compound is a research tool for studying CCR4-related immunology, including T-cell trafficking and associated inflammatory or oncology pathways.

Product Specifications

CAS Number

1957-01-3

Product Name Alternative

CCR4

Field of Research

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

99.53% (May vary between batches)

Solubility

DMSO:45 mg/mL (187.25 mM)

Smiles

N (C=1C2=C (C=CC1) C=CC=C2) C3=NC (C) =CS3

Molecular Formula

C14H12N2S

Molecular Weight

240.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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