CCR4 antagonist 3-1
CCR4 antagonist 3-1 is a small molecule inhibitor of the CCR4 chemokine receptor, demonstrating activity in vitro by blocking TARC and MDC ligand binding (IC50 = 1.7 μM) and inhibiting TARC-mediated cell migration (IC50 = 6.4 μM) . This compound is a research tool for studying CCR4-related immunology, including T-cell trafficking and associated inflammatory or oncology pathways.
Product Specifications
CAS Number
1957-01-3
Product Name Alternative
CCR4
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.53% (May vary between batches)
Solubility
DMSO:45 mg/mL (187.25 mM)
Smiles
N (C=1C2=C (C=CC1) C=CC=C2) C3=NC (C) =CS3
Molecular Formula
C14H12N2S
Molecular Weight
240.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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