N1, N11-Diethylnorspermine
N1, N11-Diethylnorspermine (DENSPM) is a polyamine analog that induces cytotoxic effects in glioblastoma multiforme (GBM) cells. It functions by potently activating SSAT and polyamine catabolism, leading to hydrogen peroxide generation, mitochondrial cytochrome c release, and caspase-3 activation. This molecule is a valuable tool for studying polyamine metabolism in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
121749-39-1
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Smiles
C (CNCCCNCC) CNCCCNCC
Molecular Formula
C13H32N4
Molecular Weight
244.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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