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N1, N11-Diethylnorspermine

N1, N11-Diethylnorspermine (DENSPM) is a polyamine analog that induces cytotoxic effects in glioblastoma multiforme (GBM) cells. It functions by potently activating SSAT and polyamine catabolism, leading to hydrogen peroxide generation, mitochondrial cytochrome c release, and caspase-3 activation. This molecule is a valuable tool for studying polyamine metabolism in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

121749-39-1

Field of Research

Cell Biology, Protein Biochemistry, Signal Transduction

Smiles

C (CNCCCNCC) CNCCCNCC

Molecular Formula

C13H32N4

Molecular Weight

244.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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