DHODH-IN-17
DHODH-IN-17 is a potent and selective inhibitor of human dihydroorotate dehydrogenase (DHODH) with an IC50 of 0.40 μM. This 2-anilino nicotinic acid compound is a valuable chemical probe for studying DHODH biology and has demonstrated research utility in models of acute myeloid leukemia (AML), both in vitro and in vivo.
Product Specifications
CAS Number
16344-26-6
Product Name Alternative
DHODH
Field of Research
Metabolism Research
Purity
99.41% (May vary between batches)
Solubility
DMSO:60 mg/mL (241.28 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.02 mM)
Smiles
OC (=O) C1=C (NC2=CC=C (Cl) C=C2) N=CC=C1
Molecular Formula
C12H9ClN2O2
Molecular Weight
248.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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