Metallo-β-lactamase-IN-2

Metallo-β-lactamase-IN-4 is a potent small-molecule inhibitor targeting key MBLs, demonstrating IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7) . It serves as a valuable research tool for studying β-lactamase-mediated resistance mechanisms and for developing combination therapies in both in vitro and in vivo antibacterial research.