Human Claudin-3 Full Length Protein (VLP)
Human Claudin-3 Full Length Protein (VLP) (CL3-H52P3) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Val 220 (Accession # O15551) .
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Specifications
This protein .
Accession Number
O15551
Expression Region
Met 1 - Val 220
Host
HEK293
Target
Claudin-3
Conjugation
Unconjugated
Tag
-
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.
Bioactivity
Immobilized Human Claudin-3 Full Length Protein (VLP) (Cat. No. CL3-H52P3) at 5 μg/mL (100 μL/well) can bind Anti-Claudin 3 Antibody, Human IgG1 with a linear range of 0.005-0.078 μg/mL (QC tested).
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
250ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CL3-H52P3.pdf
Species
Human
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