CAY10789
CAY10789 is a dual-function small molecule acting as a potent CysLT1R antagonist and a GPBAR1 agonist. It demonstrates anti-inflammatory effects in vitro by reducing U937 cell adhesion to HAECs and TNF-α expression. With favorable metabolic stability and pharmacokinetics, it is a useful research tool for studying colitis and metabolic syndromes.
Product Specifications
CAS Number
123226-28-8
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
C (OC1=CC (CO) =CC=C1) C2=NC3=C (C=C2) C=CC=C3
Molecular Formula
C17H15NO2
Molecular Weight
265.31
Storage Conditions
-20°C
Notes
For research use only.
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