LCS3
LCS3 is a reversible, non-competitive dual inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with respective IC50 values of 3.3 μM and 3.8 μM. This compound exhibits antitumor activity by inducing apoptosis and is a useful research tool for studying lung adenocarcinoma (LUAD) in both cellular and animal models.
Product Specifications
CAS Number
109844-92-0
Product Name Alternative
Cytosolic thioredoxin reductase 1 (TXNRD1), Apoptosis, Glutathione reductase, Glutathionereductase
Field of Research
Cell Biology, Metabolism Research
Purity
99.68% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (421.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15 mM)
Smiles
[O-][N+] (=O) C1=CC=C (O1) C (=O) NC1=CC=C (Cl) C=C1
Molecular Formula
C11H7ClN2O4
Molecular Weight
266.64
Storage Conditions
-20°C
Notes
For research use only.
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