DIF-3
DIF-3 is a research compound that activates GSK-3β, leading to the degradation of cyclin D1 and c-Myc and inhibition of Wnt/β-catenin signaling. It demonstrates antiproliferative effects in vitro, such as in HeLa and DLD-1 cancer cell lines, making it a tool for studying oncogenic pathways.
Product Specifications
CAS Number
113411-17-9
Product Name Alternative
GSK-3β, GSK3, betacatenin, beta-catenin, Cyclin D1, bcatenin, βcatenin, Wnt/β-catenin, Wnt, Wnt/betacatenin, Wnt/b-catenin
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (12.1 mM) ; DMSO:90 mg/mL (330.01 mM)
Smiles
CCCCCC (=O) c1c (O) cc (OC) c (Cl) c1O
Molecular Formula
C13H17ClO4
Molecular Weight
272.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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