DDO-7263
DDO-7263 is a 1,2,4-oxadiazole-based Nrf2 activator that binds to Rpn6, inhibiting 26S proteasome assembly and stabilizing ubiquitinated Nrf2. This activation of the Nrf2-ARE pathway confers anti-inflammatory activity, supporting its research use in models of oxidative stress and inflammation both in vitro and in vivo.
Product Specifications
CAS Number
2254004-96-9
Product Name Alternative
Nrf2
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
99.75% (May vary between batches)
Solubility
DMSO:16.1 mg/mL (58.92 mM) ;10% DMSO+90% Corn Oil:1.5 mg/mL (5.49 mM)
Smiles
Cc1ccc (cn1) -c1noc (n1) -c1ccc (F) c (F) c1
Molecular Formula
C14H9F2N3O
Molecular Weight
273.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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