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DDO-7263

DDO-7263 is a 1,2,4-oxadiazole-based Nrf2 activator that binds to Rpn6, inhibiting 26S proteasome assembly and stabilizing ubiquitinated Nrf2. This activation of the Nrf2-ARE pathway confers anti-inflammatory activity, supporting its research use in models of oxidative stress and inflammation both in vitro and in vivo.

Product Specifications

CAS Number

2254004-96-9

Product Name Alternative

Nrf2

Field of Research

Immunology & Inflammation, Metabolism Research

Purity

99.75% (May vary between batches)

Solubility

DMSO:16.1 mg/mL (58.92 mM) ;10% DMSO+90% Corn Oil:1.5 mg/mL (5.49 mM)

Smiles

Cc1ccc (cn1) -c1noc (n1) -c1ccc (F) c (F) c1

Molecular Formula

C14H9F2N3O

Molecular Weight

273.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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