Tubulin inhibitor 29
Tubulin inhibitor 29 (compound 3c) is a colchicine-site binder that potently disrupts microtubule assembly with an IC50 of 1.2 μM. It demonstrates antiproliferative activity, such as in MCF-7 breast cancer cells (IC50 = 7.5 μM), making it a useful chemical probe for cancer research and tubulin biology studies.
Product Specifications
CAS Number
2905-15-9
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Smiles
S (SC1=CC=C (F) C=C1) (=O) (=O) C2=CC=C (F) C=C2
Molecular Formula
C12H8F2O2S2
Molecular Weight
286.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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