A1AR antagonist 2

A1AR antagonist 2 (compound 18h) is a potent and selective human A1 adenosine receptor antagonist, with Ki values of 1.49 nM (hA1), 10.2 nM (hA2A), and 50.1 nM (hA2B) . This small molecule is a valuable research tool for investigating adenosine signaling in cardiovascular, renal, and neurological studies, both in vitro and in vivo.