CDK1/2/4-IN-1
CDK1/2/4-IN-1 (compound 3a) is a multi-cyclin-dependent kinase inhibitor with IC50 values of 1.47, 0.78, and 0.87 μM for CDK1, CDK2, and CDK4, respectively. It induces G2/M phase arrest and apoptosis in cancer cells by modulating Bax, Bcl-2, caspase-3, and p53 levels, making it a useful tool for oncology research.
Product Specifications
CAS Number
2414633-49-9
Field of Research
Cell Biology, Protein Biochemistry
Smiles
C (/C=C/C1=CC=C (OC) C=C1) (=O) C=2N=C (NC) SC2C
Molecular Formula
C15H16N2O2S
Molecular Weight
288.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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