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Aldose reductase-IN-4

Aldose reductase-IN-4 (compound IIc) is a dual inhibitor of ALR1 and ALR2, exhibiting IC50 values of 11.70 μM and 0.98 μM, respectively. This small molecule is a research tool for studying the polyol pathway in diabetic complications, applicable in both in vitro enzymatic assays and cellular models.

Product Specifications

CAS Number

2446136-17-8

Field of Research

Metabolism Research

Smiles

S (=O) (=O) (N1C=2C (C=C1) =CC=CC2) C3=CC (F) =C (O) C=C3

Molecular Formula

C14H10FNO3S

Molecular Weight

291.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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