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Nepicastat

Nepicastat (SYN117) is a brain-penetrant, orally bioavailable inhibitor of dopamine-beta-hydroxylase (DBH), exhibiting potent activity against both bovine and human enzymes with IC50 values of 8.5 nM and 9 nM, respectively. This small molecule is a valuable research tool for investigating catecholamine regulation in preclinical models of cardiovascular and neuropsychiatric disorders.

Product Specifications

CAS Number

173997-05-2

Field of Research

Metabolism Research

Smiles

C (N) C=1N ([C@@H]2CC=3C (CC2) =C (F) C=C (F) C3) C (=S) NC1

Molecular Formula

C14H15F2N3S

Molecular Weight

295.35

Storage Conditions

-20°C

Notes

For research use only.

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