Nepicastat
Nepicastat (SYN117) is a brain-penetrant, orally bioavailable inhibitor of dopamine-beta-hydroxylase (DBH), exhibiting potent activity against both bovine and human enzymes with IC50 values of 8.5 nM and 9 nM, respectively. This small molecule is a valuable research tool for investigating catecholamine regulation in preclinical models of cardiovascular and neuropsychiatric disorders.
Product Specifications
CAS Number
173997-05-2
Field of Research
Metabolism Research
Smiles
C (N) C=1N ([C@@H]2CC=3C (CC2) =C (F) C=C (F) C3) C (=S) NC1
Molecular Formula
C14H15F2N3S
Molecular Weight
295.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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