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Simufilam hydrochloride

Simufilam (PTI-125) hydrochloride is a low-toxicity, orally administered small molecule that activates filamin A (FLNA) . It is used in Alzheimer's disease research to restore normal FLNA conformation and receptor function, thereby reducing neuroinflammatory pathways associated with α7nAChR and TLR4, as demonstrated in both in vitro and in vivo studies.

Product Specifications

CAS Number

2480226-07-9

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Smiles

Cl.CN1CCC2 (CC1) NCC (=O) N2Cc1ccccc1

Molecular Formula

C15H22ClN3O

Molecular Weight

295.81

Storage Conditions

-20°C

Notes

For research use only.

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