Simufilam hydrochloride
Simufilam (PTI-125) hydrochloride is a low-toxicity, orally administered small molecule that activates filamin A (FLNA) . It is used in Alzheimer's disease research to restore normal FLNA conformation and receptor function, thereby reducing neuroinflammatory pathways associated with α7nAChR and TLR4, as demonstrated in both in vitro and in vivo studies.
Product Specifications
CAS Number
2480226-07-9
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Smiles
Cl.CN1CCC2 (CC1) NCC (=O) N2Cc1ccccc1
Molecular Formula
C15H22ClN3O
Molecular Weight
295.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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