Glutamate-5-kinase-IN-2

Glutamate-5-kinase-IN-2 is a potent inhibitor of glutamate-5-kinase (G5K) with an MIC of 4.2 μM, acting by inducing conformational changes at the enzyme's L-glutamate binding site. This compound serves as a valuable research tool for anti-tuberculosis studies, applicable in both in vitro enzymatic assays and cellular research targeting Mycobacterium tuberculosis.