Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MK-5108

MK-5108 (VX-689) is a highly selective, sub-nanomolar inhibitor of Aurora-A kinase (IC50 = 0.064 nM) . It is widely used in cancer research to study mitotic progression and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

1010085-13-8

Product Name Alternative

Inhibit, MK 5108, MK5108, MK-5108, Inhibitor, Autophagy, AuroraKinase, Aurora A, Aurora Kinase, VX 689, VX689, VX-689

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

98.76% (May vary between batches)

Solubility

DMSO:50 mg/mL (108.24 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

OC (=O) [C@@]1 (Cc2cccc (Nc3nccs3) n2) CC[C@@H] (CC1) Oc1cccc (Cl) c1F

Molecular Formula

C22H21ClFN3O3S

Molecular Weight

461.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

PLK1 (Serine/Threonine-Protein Kinase PLK1, Polo-Like Kinase 1)
488847 100 µL

PLK1 (Serine/Threonine-Protein Kinase PLK1, Polo-Like Kinase 1)

Sign In for Pricing
View Details
VNN2 Rabbit Polyclonal Antibody (Biotin)
orb448621 100 µL

VNN2 Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit
MBS2600037-01 48 Well

Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit

Sign In for Pricing
View Details
Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit
MBS2600037-02 96 Well

Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit

Sign In for Pricing
View Details
Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit
MBS2600037-03 5x 96 Well

Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit

Sign In for Pricing
View Details
Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit
MBS2600037-04 10x 96 Well

Goat E3 ubiquitin-protein ligase RAD18 (RAD18) ELISA Kit

Sign In for Pricing
View Details