MKI-1
MKI-1 is a small molecule inhibitor of MASTL kinase (IC50 = 9.9 μM) . It acts as a radiosensitizer and exhibits antitumor effects in breast cancer models by reactivating the tumor suppressor PP2A. Its activity has been demonstrated in both cellular and in vivo research studies.
Product Specifications
CAS Number
1190277-80-5
Product Name Alternative
Microtubule-associated serine/threonine kinase-like, MKI 1, MKI1, MKI-1, MASTL Kinase Inhibitor-1
Purity
99.50% (May vary between batches)
Solubility
DMSO:225 mg/mL (744.22 mM)
Smiles
O=C (Nc1nc2ccccc2[nH]1) c1cccc (c1) -n1cccc1
Molecular Formula
C18H14N4O
Molecular Weight
302.33
Storage Conditions
-20°C
Notes
For research use only.
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