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BGT226 maleate

BGT226 maleate (NVP-BGT226) is a potent dual PI3K/mTOR inhibitor, showing high activity against PI3Kα, γ, and β isoforms. It has been utilized in preclinical cancer research to study oncogenic signaling pathways and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

1245537-68-1

Product Name Alternative

PI3Kγ, PI3Kβ, PI3K, PI3Kα, Phosphoinositide 3-kinase, BGT 226, BGT 226 Maleate, BGT226, BGT-226, BGT226 Maleate, BGT226 maleate, BGT-226 maleate, BGT-226 Maleate, Autophagy, Apoptosis, NVP-BGT 226, NVP-BGT226, NVP-BGT-226, NVP-BGT226 (maleate), inhibit, mTOR, Mammalian target of Rapamycin, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

97.75% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:60 mg/mL (92.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.07 mM)

Smiles

OC (=O) \C=C/C (O) =O.COc1ccc (cn1) -c1ccc2ncc3n (C) c (=O) n (-c4ccc (N5CCNCC5) c (c4) C (F) (F) F) c3c2c1

Molecular Formula

C28H25F3N6O2·C4H4O4

Molecular Weight

650.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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