BGT226 maleate
BGT226 maleate (NVP-BGT226) is a potent dual PI3K/mTOR inhibitor, showing high activity against PI3Kα, γ, and β isoforms. It has been utilized in preclinical cancer research to study oncogenic signaling pathways and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1245537-68-1
Product Name Alternative
PI3Kγ, PI3Kβ, PI3K, PI3Kα, Phosphoinositide 3-kinase, BGT 226, BGT 226 Maleate, BGT226, BGT-226, BGT226 Maleate, BGT226 maleate, BGT-226 maleate, BGT-226 Maleate, Autophagy, Apoptosis, NVP-BGT 226, NVP-BGT226, NVP-BGT-226, NVP-BGT226 (maleate), inhibit, mTOR, Mammalian target of Rapamycin, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
97.75% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:60 mg/mL (92.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.07 mM)
Smiles
OC (=O) \C=C/C (O) =O.COc1ccc (cn1) -c1ccc2ncc3n (C) c (=O) n (-c4ccc (N5CCNCC5) c (c4) C (F) (F) F) c3c2c1
Molecular Formula
C28H25F3N6O2·C4H4O4
Molecular Weight
650.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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