A2A/A1 AR antagonist-1

A2A/A1 AR antagonist-1 (compound 1a) is a potent dual antagonist of adenosine A2A and A1 receptors, exhibiting Kis of 5.58 nM and 24.2 nM, respectively. It is a valuable research tool for investigating neuroprotective strategies in models of ischemic stroke, applicable in both in vitro and in vivo experimental settings.