Nerve Growth Factor Receptor, p75NTR - FITC (Low-affinity NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR)

For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 °C. Aliquots are stable for at least 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.

Recognizes the extracellular domain of the neurotrophin receptor p75NTR in rat. May be used for immunocytochemical localisation of rat cells expressing p75NTR, ELISA and western blot. This antibody has also been used for the construction of the MC192-saporin immunotoxin for specific elimination of neuronal populations in basal forebrain cholinergic neurons to generate an animal model for Alzheimer's disease. Does not react with mouse

[nerve growth factor receptor; nerve growth factor receptor; NRH; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor]