IRAK4-IN-11

IRAK4-IN-11 is a highly potent and cell-active IRAK4 inhibitor, demonstrating an enzymatic IC50 of 8 nM and a cellular pIRAK4 IC50 of 190 nM. This small molecule is a valuable research tool for investigating IRAK4 signaling in immunological and oncological contexts, applicable in both in vitro and in vivo studies.