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ERCC1-XPF-IN-2

ERCC1-XPF-IN-2 is a potent small molecule inhibitor of the ERCC1-XPF endonuclease, exhibiting an IC50 of 0.6 μM. It is active in nucleotide excision repair and cisplatin enhancement assays, and its utility in DNA damage response research is supported by activity in γH2AX-based cellular models.

Product Specifications

CAS Number

1808986-37-9

Product Name Alternative

Endonuclease

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Purity

98.21% (May vary between batches)

Solubility

DMSO:225 mg/mL (689.82 mM)

Smiles

Oc1ccc (CNC (=O) Cc2ccc (Cl) cc2Cl) cc1O

Molecular Formula

C15H13Cl2NO3

Molecular Weight

326.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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