ERCC1-XPF-IN-2
ERCC1-XPF-IN-2 is a potent small molecule inhibitor of the ERCC1-XPF endonuclease, exhibiting an IC50 of 0.6 μM. It is active in nucleotide excision repair and cisplatin enhancement assays, and its utility in DNA damage response research is supported by activity in γH2AX-based cellular models.
Product Specifications
CAS Number
1808986-37-9
Product Name Alternative
Endonuclease
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.21% (May vary between batches)
Solubility
DMSO:225 mg/mL (689.82 mM)
Smiles
Oc1ccc (CNC (=O) Cc2ccc (Cl) cc2Cl) cc1O
Molecular Formula
C15H13Cl2NO3
Molecular Weight
326.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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