THK-5117
THK-5117 is an arylquinoline-based compound developed as a PET imaging agent targeting tau pathology. It exhibits high affinity (Ki = 10.5 nM) for tau fibrils and aggregates, including those in Alzheimer's disease brain homogenates, supporting its use in both in vitro binding assays and in vivo neuroimaging research.
Product Specifications
CAS Number
1374107-54-6
Field of Research
Signal Transduction
Smiles
O (CC (CF) O) C1=CC2=C (N=C (C=C2) C3=CC=C (NC) C=C3) C=C1
Molecular Formula
C19H19FN2O2
Molecular Weight
326.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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