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PDE4-IN-8

PDE4-IN-8 is a highly potent and selective PDE4B2 inhibitor with an IC50 of 0.93 nM, showing significantly less activity against IL13, IL4, and IFNγ. This selectivity profile makes it a valuable research tool for investigating PDE4-mediated pathways in inflammatory and autoimmune diseases in both cellular and animal models.

Product Specifications

CAS Number

2415085-45-7

Field of Research

Immunology & Inflammation, Metabolism Research, Signal Transduction

Smiles

O (CCC) C=1C=C (C=CC1OC) C=2C=C (C=NC2) [C@@H]3CB (O) OC3

Molecular Formula

C18H22BNO4

Molecular Weight

327.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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