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Verosudil

Verosudil (AR-12286) is a potent ROCK inhibitor with Ki values of 2 nM for both ROCK1 and ROCK2. It lowers intraocular pressure by enhancing trabecular meshwork outflow, as demonstrated in steroid-induced ocular hypertension models in mice, supporting research in glaucoma pathophysiology.

Product Specifications

CAS Number

1414854-42-4

Product Name Alternative

AR 12286, AR12286, AR-12286, ROCK1, ROCK2, Verosudil

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.68% (May vary between batches)

Solubility

DMSO:45 mg/mL (137.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.05 mM)

Smiles

CN (C) C (C (=O) Nc1ccc2c (cc[nH]c2=O) c1) c1ccsc1

Molecular Formula

C17H17N3O2S

Molecular Weight

327.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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