PDE4-IN-9
PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an in vitro IC50 of 1.4 μM, demonstrating superior enzymatic inhibition to rolipram. It exhibits significant in vivo efficacy in LPS-induced models of asthma, COPD, and sepsis, supporting its research utility in inflammatory and pulmonary disease studies.
Product Specifications
CAS Number
2519450-32-7
Field of Research
Metabolism Research, Signal Transduction
Smiles
C (=O) (C=1N=C (OC1) C2=CC=C (OC) C=C2) N3\C (=N\C#N) \SCC3
Molecular Formula
C15H12N4O3S
Molecular Weight
328.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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