DL-threo-PDMP (hydrochloride)
DL-threo-PDMP hydrochloride is the hydrochloride form of DL-threo-PDMP that is a competitive glucosylceramide synthase (GCS) inhibitor. DL-threo-PDMP resensitizes refractory testicular germ cell tumors and epithelial ovarian cancer orthoxenografts to cisplatin in mice[1].
Product Specifications
CAS Number
80938-69-8
Product Name Alternative
4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007
UNSPSC
12352005
Target
Glucosylceramide Synthase (GCS)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dl-threo-pdmp-hydrochloride.html
Purity
99.40
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H](C1=CC=CC=C1)[C@H](NC(CCCCCCCCC)=O)CN2CCOCC2.Cl
Molecular Formula
C23H39ClN2O3
Molecular Weight
427.02
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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