Synaptopodin (SYNPO, KIAA1029)

Lyophilized powder may be stored at -20 °C. Stable for 12 months at -20 °C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 °C. Reconstituted product is stable for 12 months at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 

Recognizes rat synaptopodin at ~44kD (degradation product). Species Crossreactivity: human, bovine, guinea pig, mouse, and gerbil. Does not recognize rabbit, frog or chicken. Recognizes differentiated podocytes (glomerular visceral epithelial cells) in vivo and in vitro (weaker additional reaction with arterial endothelial cells); co-localizes with a-actinin. Does not react with parietal cells. Reacts with a subset of exclusively telencephalic synapses. Differentiation-dependent expression in cultured hippocampal neurons and during postnatal maturation of rat brain.