Bezuclastinib
Bezuclastinib (CGT9486) is a potent and selective inhibitor targeting the tyrosine kinase c-KIT, specifically its D816V mutation implicated in advanced systemic mastocytosis. It demonstrates efficacy in both cellular assays and animal models, supporting its investigation for this and related oncologic research applications.
Product Specifications
CAS Number
1616385-51-3
Product Name Alternative
CGT9486, cKit, c-Kit (D816V), PLX 9486
Field of Research
Signal Transduction
Purity
99.55% (May vary between batches)
Solubility
DMSO:70 mg/mL (211.24 mM)
Smiles
Cc1[nH]nc (C (=O) Nc2cnc3[nH]c (cc3c2) -c2ccccc2) c1C
Molecular Formula
C19H17N5O
Molecular Weight
331.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-61473R-APC-Cy7 100 µL
PRKAR2B Recombinant Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details 
220648-01 50 µL
AKAP8 (A-Kinase anchor Protein 8, AKAP-8, A-Kinase anchor Protein 95kD, AKAP 95, AKAP 8, AKAP95, AKAP-95) discontinued
Sign In for Pricing
View Details 220648-02 100 µL
AKAP8 (A-Kinase anchor Protein 8, AKAP-8, A-Kinase anchor Protein 95kD, AKAP 95, AKAP 8, AKAP95, AKAP-95) discontinued
Sign In for Pricing
View Details A16236-Cy3 100 µg/Vial
Anti-SLC23A3 Antibody Picoband® Cy3 Conjugated
Sign In for Pricing
View Details